31 Jan MPH501 Quantitative Methods for
MPH501 Quantitative Methods for Public Health Application
Module 2 Exercise
Question 1 A cohort study is conducted to assess the association between clinical characteristics and the risk of stroke. The study involves n=1,250 participants who are free of stroke at the study start. Each participant is assessed at study start (baseline) and every year thereafter for five years. The following table displays data on hypertension status measured at baseline and hypertension status measured two years later.
2 Years: Not Hypertensive 2 Years: Hypertensive
Baseline: Not Hypertensive 850 148
Baseline: Hypertensive 45 207
a. Compute the prevalence of hypertension at baseline.
b. Compute the prevalence of hypertension at 2 years.
c. Compute the cumulative incidence of hypertension over 2 years.
Question 2A randomized trial is conducted to evaluate the efficacy of a new cholesterol lowering medication. The primary outcome is incident coronary artery disease. Participants are free of coronary artery disease at the start of the study and randomized to receive either the new medication or a placebo. Participants are followed for a maximum of 10 years for the development of coronary artery disease. The following data are observed.
Number of Participants Number with Coronary Artery Disease
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